Spontaneous buckling of contractile poroelastic actomyosin sheets
نویسندگان
چکیده
منابع مشابه
Contractile units in disordered actomyosin bundles arise from F-actin buckling.
Bundles of filaments and motors are central to contractility in cells. The classic example is striated muscle, where actomyosin contractility is mediated by highly organized sarcomeres which act as fundamental contractile units. However, many contractile bundles in vivo and in vitro lack sarcomeric organization. Here we propose a model for how contractility can arise in bundles without sarcomer...
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1. Surface-spread actomyosin, compressed into fibers, shows biological properties of contractility and enzymic activity. 2. In unloaded contractions, wet and dry weight determinations show no appreciable water loss in contraction. The fibers also evince a strong ATP-ase activity. 3. A structural continuity in the fibers by intermolecular linkages of the component actomyosin molecules is establi...
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The actomyosin cell cortex is an active contractile material for driving cell- and tissue morphogenesis. The cortex has a tendency to form a pattern of myosin foci, which is a signature of potentially unstable behavior. How a system that is prone to such instabilities can rveliably drive morphogenesis remains an outstanding question. Here, we report that in the Caenorhabditis elegans zygote, fe...
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ژورنال
عنوان ژورنال: Nature Communications
سال: 2018
ISSN: 2041-1723
DOI: 10.1038/s41467-018-04829-x